Faculty

 
Alexander

Kathleen A. Alexander,
Associate Professor

B.S., University of California, Davis (1982)
D.V.M., University of California, Davis (1994)
Ph.D., University of California, Davis (1995)
kathyalx@vt.edu
152 Cheatham Hall

Google Scholar Profile

Overview of Focus

My research program is directed at exploring and understanding the factors that influence the emergence and persistence of emerging and re-emerging diseases at the human- wildlife interface. My program embraces a systems biology approach to ecosystem health integrated with public health, beginning within host - pathogen dynamics and extending to the rural livelihoods of communities living with wildlife, including the impact on ecosystem function and local communities themselves.

Courses Taught

Disease Ecology & Ecosystem Management
Advanced Topics in Disease Ecology

Learn more about the Alexander Lab Group

News


Outreach and Research in Botswana


To Learn More About the Alexander Lab Group Click Here

molecular lab

Dr. Alexander has established a field laboratory in her study site in Northern Botswana which has both molecular genetics and bacteriological investigations capacity-the first of its kind in the region. The focus of her work is directed at understanding disease transmission dynamics at the human-wildlife interface. In Botswana, Risa Pesapane, previous graduate student, processes DNA from bacteria cultured from banded mongoose fecal samples.


Dr. Alexander's Postdoctoral Associates & Students

J. Fox
John Tyler Fox, PhD Student
Claire Sanderson, Postdoctoral Associate
 

 


Select Publications

  1. Lofgren E., Halloran M.E., Rivers C.M., Drake J.M., Porco T.C., Lewis B., Yang W., Vespignani A., Shaman J., Eisenberg J.N.S., Eisenberg M.C., Marathe M., Scarpino S.V., Alexander K.A., Meza R., Ferrari M.J., Hyman J.H., Meyers L.A., S. Eubank. 2014. MATHEMATICAL MODELS: A KEY TOOL FOR OUTBREAK RESPONSE. PNAS, doi:10.1073/pnas.1421551111

  2.  Alexander, K.A.Sanderson, C.E.*, Marathe, M., Lewis, B.L., Rivers, C.M., Shaman, J., Drake, J.M., Lofgren, E., Dato, V.M., Eisenberg, M.C., and S. Eubank. 2014.What factors might have led to the emergence of Ebola in West Africa? Plos Neglected Tropical Diseases.Conditionally accepted.
  3. Rivers, C., Alexander, K.A., Bellan, S., Del Valle, S., Drake, J.M. Eisenberg, J.N.S., Eubank, S., Ferrari, M., Halloran, M.E., Galvani, A., Lewis, B.L., Lewnard, J., Lofgren, E., Macal, C., Marathe, M., Ndeffo Mbah, M.L., Ancel Meyers, L.,  Meza, R., Park, A., Porco,T., Scarpino, S.M., Shaman, J., Vespignani, A., and W.  Yang. 2014. Models overestimate Ebola cases: More than forecastsNature, 515(7528):492. DOI:10.1038/515492a
  4. Fairbanks, B.M.*, Hawley, D.M., and K.A. Alexander. 2014. No evidence for avoidance of visibly diseased conspecifics in the highly social banded mongoose (Mungos mungo). Behavioral Ecology and Sociobiology.  Accepted for publication.
  5. Halloran M.E., Vespignani A., Bharti N., Feldstein L.R., Alexander K.A., Ferrari M., Shaman J., Drake J.M., Porco T., Eisenberg J.N., Del Valle S.Y., Lofgren E., Scarpino S.V., Eisenberg M.C., Gao D., Hyman J.M., Eubank S., Longini I.M. Jr. 2014. EBOLA: MOBILITY DATA, Science Oct 24:346(6208):433.

  6. Alexander K.A., and C.E. Sanderson. 2014. CONSERVING CARNIVORES: MORE THAN NUMBERSScience Mar 14:343(6176):1199.

  7. Blackburn, JK. Diamond, U., Kracalik, IT, Widmer, J., Brown, W.,Morrissey, B.D., Alexander, K.A, Curtis, A.J., Ali, A., and J.G. Morris.  2014. HOUSEHOLD-LEVEL SPATIOTEMPORAL PATTERNS OF INCIDENCE OF CHOLERA, Haiti, 2011. Emerg Infect Dishttp://dx.doi.org/10.3201/eid2009.131882

  8.  Fairbanks, B.M., Hawley, D.M., and K.A. Alexander. 2014. THE IMPACT OF HEALTH STATUS ON DISPERSAL BEHAVIOR IN BANDED MONGOOSES (Mungo mungo), EcoHealth: Volume 11, Issue 2 (2014), Page 258-262.       

  9. Blackburn, J.K., Asher, V., Stokke, S., Hunter, D.L., andK.A. Alexander. DANCES WITH ANTHRAX: WOLVES, CANIS LUPUS, KILL ANTHRAX BACTEREMIC BISON IN SOUTHWESTERN MONTANA, , Journal of Wildlife Research, Vol. 50, No. 2, pp. 393-396.

  10. Sanderson, C.E.,* Jobbins, S.E.*, and K.A. Alexander2013. FOR THE SOCIAL CARNIVORE, LIFE IS COMPLICATED.. Population Ecology, DOI: 10.1007/s10144-013-0410-5.               

  11. Bagamian, K.H.,  Alexander, K.A.,  Hadfield,T.L.,  and Blackburn J.K.. 2013. ANTE-AND POSTMORTEM DIAGNOSTIC TECHNIQUES FOR ANTHRAX: RETHINKING PATHOGEN EXPOSURE AND THE GEOGRAPHIC EXTENT OF THE DISEASE IN WILDLIFE. Journal of Wildlife Diseases. 49(4):786-801.

  12. Sanderson, C.E., Jobbins, S.E., and K.A. Alexander2013. FOR THE SOCIAL CARNIVORE, LIFE IS COMPLICATED. Population Ecology, 2013:1-9.
  13. Alexander, K.A., and J.K. Blackburn. 2013. OVERCOMING BARRIERS IN EVALUATING OUTBREAKS OF DIARRHEAL DISEASE IN RESOURCE POOR SETTINGS: ASSESSMENT OF RECURRENT OUTBREAKS IN CHOBE DISTRICT, BOTSWANA. BMC Public Health, 13:775.
  14. Jobbins, S.E., Sanderson, C.E., and K.A. Alexander. 2013. LEPTOSPIRA INTERROGANS AT THE HUMAN WILDLIFE INTERFACE IN NORTHERN BOTSWANA: A NEWLY IDENTIFIED PUBLIC HEALTH THREATZoonoses and Public Health, DOI: 10.1111/zph.12052
  15. Alexander, K.A., Carzolio, M., Goodin, D. and E. Vance. 2013. CLIMATE CHANGE IS LIKEL TO WORSEN THE PUBLIC HYEALTH THREAT OF DIARRHEAL DISEASE IN BOTSWANA. Int. J. Environ. Res. Public Health. 10, 1202-1230.
  16. Pesapane R., Ponder M., and K.A. Alexander. 2013. TRACKING PATHOGEN TRANSMISSION AT THE HUMAN-WILDLIFE INTERFACE: BANDED MONGOOSE AND ESCHERICIA COLI. EcoHealth.
  17. Alexander, K.A., Herbein, J., and A. Zajac. 2012. THE OCCURRENCE OF CRYPTOSPORIDIUM AND GIARDIA INFECTIONS AMONG PATIENTS REPORTING DIARRHEAL DISEASE IN CHOBE DISTRICT, BOTSWANA. Advances in Infectious Disease. 2, 143-147.

  18. Alexander, K.A. Lewis, B., Madav, M. Eubank, S. and J.K. Blackburn. 2012. MODELING OF WILDLIFE ASSOCIATED ZOONOSES: APPLICATIONS AND CAVEATS. Vector-Borne and Zoonotic Diseases. 12(12): 1005-1018.

  19. Alexander, K.A., Blackburn J.K., Vandewalle M.E., Pesapane R., Baipoledi E.K., and P.H. Elzer. 2012. BUFFALO, BUSH MEAT, AND THE ZOONOTIC THREAT OF BRUCELLOSIS IN BOTSWANA. PLoS ONE 7(3):e32842.

  20. Laver, P., Ganswindt, A., Ganswindt, S., and K.A. Alexander. 2011 . NON-INVASIVE MONITORING OF GLUCOCORTICOID METABOLITES IN BANDED MONGOOSES (MUNGOS MUNGO) IN RESPONSE TO PHYSIOLOGICAL AND BIOLOGICAL CHALLENGES.  General and Comparative Endocrinology. 179[2]: 178-183.

  21. Alexander, K.A., Blackburn, J.K.,Frimpong, E.A. 2011.BUFFALO AND MASLOW'S HAMMER, AND THE ECOLOGIST'S STATISTICAL TOOLBOX. Frontiers in Ecology and the Environment. 9: 302–303.
    doi:10.1890/1540-9295-9.5.302
  22. Alexander, K.A., McNutt, J.W. 2010. Human behavior CAN INFLUENCE THE EMERGENCE OF INFECTIOUS DISEASE AT THE HUMAN-WILDLIFE INTERFACE. Frontiers in Ecology and Environment. 8: 522-526.

  23. Alexander, K.A. Laver, P. N., Michel, A.L., Williams, M., van Helden, P.D., Warren, R.M., and N.C. Gey van Pittius. 2010. THE EMERGENCE OF A PREVIOUSLY UNIDENTIFIED MYCOBACTERIUM TUBERCULOSIS COMPLEX PATHOGEN, M. MUNGI, SP NOV. Emerging Infectious Diseases. 16(8):1296 - 1299.
  24. Alexander K.A., McNutt, J.W., Briggs, M.B., Stander, P.E., Funston, P., Hemson, G., Keet, D., and M van Vuuren. 2010. MULTI-HOST PATHOGENS AND CARNIVORE MANAGEMENT IN SOUTHERN AFRICA. Comparative Immunology, Microbiology and Infectious Diseases. 33(3):249 - 265.
  25. Alexander, K.A. 2010. NOVEL TUBERCULOSIS COMPLEX PATHOGEN, M. MUNGI. Emerging Infectious Diseases. 16[8]: 1296-1299.
  26. Roelke, M. E., Brown, M.A., Troyer, J. L.,Winterbach, H. WInterbach, C., Hemson, G., Smith, D., Johnson, R.C., Pecon-Slattery, J., Roca, A.L., Alexander, K.A., Klein, L., Martelli, P., Krishnasamy, K., and S.J. O'Brien. 2009. Pathological manifestations of feline immunodeficiency virus (FIV) infection in wild African lions. Virology. 390 [1]: 1-12.

  27. Alexander, K.A. 2009. Successful intervention in a disease outbreak in the endangered Iberian lynx: what can we learn? Animal Conservation. 12[3]:183-184.

  28. Antunes, A., Troye, J.L., Roelke, M.E., Pecon-Slattery, .J, Packer, C., Winterbach, C., Winterbach, H., Hemson, G., Frank, L., Stander, P., Siefert, L., Driciru, M., Funston, P., Alexnader, K.A., Prager, K.C., Mills, G., Wildt, D., Bush, M., O'Brien, S.J., and W.E. Johnson. 2008. The Evolutionary Dynamics of the Lion Panthera leo Revealed by Host and Viral Population Genomics. Plos Genetics. 4[11].

  29. Troyer, J.L, Pecon-Slattery, J. Roelke, M.E., Johnson, W., VandeWoude, S., Vazquez-Salat, N., Brown, M., Frank, L., Woodroffe, R., WInterbach, C., Winterbach, H., Hemson, G., Bush, M., Alexander, K.A., and S.J. O'Brien. 2005. Seroprevalence and genomic divergence of circulating strains of Feline immunodeficiency virus among Felidae and Hyaenidae species. Journal of Virology. 79[13]: 8282-8294.

  30. Alexander, K.A., Pleydell, E., Williams, M., Nyange, J.F.C., and A.L. Michel. 2002. MYCOBACTERIUM TUBERCULOSIS: AN EMERGIN DISEASE OF FREE-RANGING WILDLIFE. Emerging Infectious Diseases. 8(6):598 - 601.
  31. Penzhorn, B.L., Stylianides, E., van Vuuren, M., Alexander, K.A, Meltzer D.G.A., and N. Mukarati. 2002. SEROPREVALENCE OF TOXOPLASMA GONDII IN FREE-RANGING LION AND LEOPARD POPULATIONS IN SOUTHERN AFRICA. South African Journal of Wildlife Research. 32(2):163 - 165.
  32. Alexander, K.A., Kat, P.W., Munson, L.A., Kalake, A. and M.J1996. Canine distemper-related mortality among wild dogs (Lycaon pictus) in Chobe national park, Botswana. Journal of Zoo and Wildlife Medicine. 27[3]: 426-427.

  33. Kat, P.W., Alexander, K.A., Smith, J.S., Richardson, J.D., and L. Munson. 1996. Rabies among African wild dogs (Lycaon pictus) in the Masai Mara, Kenya. Journal of Veterinary Diagnostic Investigation. 8[4]: 420-426.

  34. House, C., Alexander, K.A., Kat, P.W., O'Brien, S.J., and J. Mangiafico. 1996. Serum antibody to Rift Valley fever virus in African carnivores. Annals of the New York Academy of Science. 791:345-349.

  35. Ginsbert, J.R., Alexander, K.A., Creel, S., Kat, P.W., McNutt, J.W. and M.G.L Mills. 1995. HANDLING AND SURVIVORSHIP OF AFRICAN WILD DOG (LYCAON-PICTUS) IN 5 ECOSYSTEMS. Conservation Biology. 9 [3]:665-674.

  36. Alexander, K.A., Kat, P.W. Frank, L.G., Holekamp, K.E., Smale, L., House, C. and M.J.G. Appel. 1995. Evidence of canine distemper virus infection among free-ranging spotted hyenas (Crocuta crocuta) in the Masai Mara, Kenya. Journal of Zoo and Wildlife Medicine. 26[2]: 201-206.

  37. Alexander, K.A., Kat, P.W., House, J., Laurenson, M.K., McNutt, J.W., O'Brien, S.J., and B.I. Osburn. 1995. AFRICAN HORSE SICKNESS AND AFRICAN CARNIVORES. Veterinary Microbiology. 47 [1-2]: 133-140.
  38. Kat, P.W., Alexander, K.A., Smith, J.S. and L. Munson. 1995. RABIES AND AFRICAN WILD DOGS IN KENYA. Proceedings of the Royal Society of London Series B-Biological Sciences. 262[1364]:229-233.

  39. Alexander, K.A., Appel, M.J.G. 1994. AFRICAN WILD DOGS (LYCAON-PICTUS) ENDANGERED BY A CANINE-DISTEMPER EPIZOOTIC AMONG DOMESTIC DOGS NEAR THE MASAI-MARA NATIONAL RESERVE, KENYA. Journal of Wildlife Diseases. 30[4]:481-485.

  40. Alexander, K.A., Kat, P.W., Wayne, R.K., and T.K. Fuller. 1994. SEROLOGIC SURVEY OF SELECTED CANINE PATHOGENS AMONG FREE-RANGING JACKALS IN KENYA. Journal of Wildlife Diseases. 30[4]: 486-491.

  41. Alexander, K.A., Maclachlan, N.J., Kat, P.W., House, C., O'Brien, S.J., Lerche, N.W., Sawyer, M., Frank, L.G., Holekamp, K., Smale, L., McNutt, J.W., Laurenson, K., Mills, M.G.L., and B.I. Osburn. 1994. EVIDENCE OF NATURAL BLUETONGUE VIRUS-INFECTION AMONG AFRICAN CARNIVORES. American Journal of Tropical Medicine and Hygiene. 51[5]: 568-576.

  42. Alexander, K.A., Conrad, P.A., Gardner, I., Parish, C., Appel, M., Levy, M.G., Lerche, N., and P.W. Kat. 1993. SEROLOGIC SURVEY FOR SELECTED MICROBIAL PATHOGENS IN AFRICAN WILD DOGS (LYCAON-PICTUS) AND SYMPATRIC DOMESTIC DOGS (CANIS-FAMILIARIS) IN MAASAI-MARA, KENYA. Journal of Zoo and Wildlife Medicine. 24[2]:140-144.

  43. Alexander, K.A., Smith, J.S., Macharia, M.J., and A. King. 1993. RABIES IN THE MASAI-MARA, KENYA - PRELIMINARY-REPORT. Onderstepoort Journal of Veterinary Research. 60 [4]:411-414.

  44. Alexander, K.A., Richardson, J.D., and P.W. Kat. DISEASE AND CONSERVATION OF AFRICAN WILD DOGS. 1992. Swara, 15:13 - 15.